Buffalo Bills quarterback Josh Allen could become his team's sole all-time leading touchdown scorer in Week 13.

SportsLine's model has simulated San Francisco vs. Buffalo on Sunday Night Football 10,000 times and revealed its SNF picks ...

Coming into the 2024 NFL season, it wouldn't have been out of the ordinary to find a Super Bowl prediction featuring the ...

Following new injury reports, updated simulations reveal the best bet for 49ers vs. Bills on Sunday Night Football. Injury ...

The San Francisco 49ers battle the Buffalo Bills at 5:20 p.m. PDT on Sunday, Dec. 1 at Highmark  Stadium in Orchard Park, N.Y ...

The Game Matchups Preview series is dedicated to breaking down how the Buffalo Bills match up with their opponent in every ...

Running back Christian McCaffrey says the San Francisco 49ers are "hungry" to make a playoff push even with the defending NFC ...

The San Francisco 49ers have released their final injury report ahead of their Week 13 bout with the Buffalo Bills.

A good ol' fashioned lake effect snowstorm is burying western New York this weekend when the Buffalo Bills and San Francisco ...

In January, a lake-effect storm forced the NFL to push back the Bills' wild-card playoff home game against Pittsburgh by a ...

Brock Purdy speaks with reporters ahead of San Francisco's Week 13 matchup against the Buffalo Bills on Sunday night.49ers QB ...