The Lions kick off a busy NFL Week 13 against Chicago on Thursday. Contenders Kansas City, Green Bay, Buffalo, Denver and ...

George Kittle will lead the San Francisco 49ers into their matchup versus the Buffalo Bills at Highmark Stadium on Sunday at ...

While the 49ers look like an easy opponent, San Francisco's health could be a major factor in the game, warns one NFL expert.

The San Francisco 49ers explored signing Tom Brady ahead of the 2023 season, a consideration that could repeat itself this ...

San Francisco 49ers defensive end Nick Bosa (hip/oblique) was pulled from his team's Week 11 loss to the Seattle Seahawks due ...

Buffalo Bills look to extend its six-game win streak as Josh Allen faces an unfamiliar foe in the San Francisco 49ers at ...

If the Bills do clinch the AFC East on Sunday, they'd be the earliest team to win a division since the New Orleans Saints won ...

Our top pick for the 49ers vs. Bills Week 13 NFL matchup is to bet on the 49ers +6.5 (+100). This betting advice is ...

The Buffalo Bills' home-field advantage will once again be on display on Sunday night with severe weather projected to be on ...

Seahawks All Access takes you on the field and the sidelines with all the sights and sounds from the team's Week 12 win over ...

Being without Brock Purdy against the Green Bay Packers stung the San Francisco 49ers. It essentially chalked up the game as ...

Buffalo (9-2) will return to action on Sunday night when they host the San Francisco 49ers (5-6). The Bills are perfect ...