Playing defense was optional for the San Francisco 49ers and the Indianapolis Colts on Monday night. The vast majority of the game was dominated by offensive hi

George Kittle won't practice on Wednesday due to an ankle injury, but he has a chance to play vs. the Bears. Ricky Pearsall will be limited.

San Francisco 49ers wide receiver Kendrick Bourne hit one of his incentives in his contract during the team's win over the Indianapolis Colts, making $500,000.

Philip Rivers starts again when he takes on the ferocious 49ers on "Monday Night Football." Here's score, highlights, stats and more for Colts-49ers.

The San Francisco 49ers have been one of the most injured teams thoughout the entire 2025 season. While the team will never get completely healthy, it is signif

The San Francisco 49ers beat the Indianapolis Colts 48-27, led by Brock Purdy’s 5 TDs. Colin Cowherd asks if the now 11-4 49ers are serious title contenders.

Here's how to watch the Bears this Sunday, as they return to primetime against a contending San Francisco 49ers team.

In the final game of what has been a wild Week 16, the Indianapolis Colts host the San Francisco 49ers on "Monday Night Football." The Colts come into this game starting 44-year-old Philip Rivers at quarterback after the season-ending Achilles injury to Daniel Jones.