Returning from a grueling injury, the All-Pro linebacker anchored a dominant defensive showcase in Australia, silencing the Rams and proving he remains the Niners' definitive championship X-factor.

The real phantom of the opera is wages as San Francisco Opera musicians go on strike during opening night. See more.

The 49ers and Rams are going head-to-head in the NFL's first game in Australia. Follow along here for updates.

What’s at stake, injuries, key matchup, TV info, fantasy sleeper and prediction for Thursday night’s season opener Down Under in Melbourne, Australia.

George Kittle suffered a torn Achilles in January. Is he ready to go against the Rams now that it's September?

Kyle Shanahan didn't just pick up a win during the San Francisco 49ers' recent road trip to Melbourne, Australia. The 10th-year head coach got himself a new deal.

The San Francisco 49ers have received the final George Kittle injury update ahead of their Week 1 matchup against the Los Angeles Rams on Thursday evening in the NFL’s opening weekend. According to ESPN’s Adam Schefter,

Who do the San Francisco 49ers play next game? When do they play? What to know about team's NFL Week 2 schedule, with date, time, location, opponent.

Brock Purdy, Mike Evans and Fred Warner led the San Francisco 49ers past the Los Angeles Rams, while Matthew Stafford and Myles Garrett struggled badly.

Sibling superstar group the Jonas Brothers will perform at half-time of the NFL Melbourne match between the LA Rams and San Francisco 49ers at the MCG on Friday, September 11 AEST (Thursday, September 10 ET). Any other support acts are yet to be revealed or announced.

San Francisco 49ers star LB Fred Warner joined "The Pivot" podcast and recalled the "foolish" conversation he had on sidelines during Super Bowl LIV.