Intravenous thrombolysis remains a standard treatment for acute ischemic stroke within 4.5 hours after onset. Vascular reocclusion may occur after intravenous thrombolysis and may be preventable ...

In the current anti-immigrant political environment in the United States, what will happen when immigrants who work in the health care system are forced to leave?

The financial assistance policies of some U.S. hospitals now define medical necessity much more restrictively than it has conventionally been understood, as covering only services that are ...

Musunuru and colleagues1 describe in the Journal an innovative approach in which gene editing is applied in the treatment of a very rare disease, the severe urea-cycle disorder carbamoyl-phosphate ...

Corporatization” of health care, a process predicted decades ago, now refers to the general trend throughout the industry toward higher levels of integrated control by consolidated profit-seeking ...

To the Editor: The study by Devamani et al. (March 12 issue)1 of the incidence of scrub typhus in rural South India presents several methodologic considerations that warrant careful attention. Firs ...

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Explore a collection of articles and other resources on the Coronavirus (Covid-19) outbreak, including clinical reports, management guidelines, and commentary.

Hairy-cell leukemia, a rare B-cell cancer driven by a BRAF mutation and manifesting with cytopenias and splenomegaly, is responsive to purine analogue chemotherapy and to BRAF inhibitors combined w ...

Hereditary angioedema is a rare genetic disease that may include recurrent attacks of cutaneous angioedema, severe abdominal pain, and airway compromise. Prophylaxis and treatment include C1 inhibi ...

On January 2, 2022, Israel began administering a fourth dose of BNT162b2 vaccine to persons 60 years of age or older. Data are needed regarding the effect of the fourth dose on rates of confirmed s ...

Acute kidney injury is associated with many short- and long-term adverse events. This review considers the cardiovascular consequences and strategies that can be used during acute kidney injury ...