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  1. mTOR - Wikipedia

    Mammalian target of rapamycin (mTOR) is a kinase that regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis, autophagy, and transcription. [5][6] It also …

  2. mTOR signaling networks: mechanistic insights and translational ...

    Dec 30, 2025 · The mammalian target of rapamycin (mTOR) pathway is a central regulator of cellular growth, metabolism, and homeostasis, integrating a wide array of intracellular and …

  3. What Is mTOR Signaling and Why Is It Important?

    Aug 5, 2025 · It acts as a central hub, sensing the cell’s internal and external environment to regulate growth, metabolism, and survival. By integrating various signals, mTOR helps …

  4. The mTOR Signaling Pathway: Key Regulator and Therapeutic …

    Notably, mTOR plays a pivotal role in cardiovascular health and disease, particularly in the onset and progression of cardiac conditions. In this review, we discuss mTOR’s structure and …

  5. mTOR Signaling | Cell Signaling Technology

    3 days ago · Discover the mTOR pathway and its role in cellular growth and metabolism. Click here to explore the intricacies of this vital signaling pathway.

  6. MTOR gene: MedlinePlus Genetics

    The MTOR gene provides instructions for making a protein called mTOR. Learn about this gene and related health conditions.

  7. Discovery – Targeted Treatments and mTOR Inhibitors

    The target of rapamycin (known as mTOR or the mechanistic target of rapamycin) is a protein that tells cells when to grow, divide, and survive. mTOR often mutates in cancer cells, leading to …

  8. mTOR: Its Critical Role in Metabolic Diseases, Cancer, and the

    Jun 2, 2024 · The mammalian target of rapamycin (mTOR) is a pivotal regulator, integrating diverse environmental signals to control fundamental cellular functions, such as protein …

  9. More TOR: The expanding role of mTOR in regulating immune …

    Jul 8, 2025 · The mammalian/mechanistic target of rapamycin (mTOR) is an evolutionarily conserved multi-node signaling pathway that integrates critical environmental cues to control …

  10. Structural mechanisms of the mTOR pathway - ScienceDirect

    Oct 1, 2023 · Abstract The mTOR signaling pathway is essential for regulating cell growth and mammalian metabolism. The mTOR kinase forms two complexes, mTORC1 and mTORC2, …