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Through a silver(i)-catalysed synthesis, disubstituted cuneane analogues have been reported by Journal of the American Chemical Society (https://hubs.ly/Q020H7z40). CSD entry YIMHAH is formed via the rearrangement of a 1,4-disubstituted cubane derivative. These analogues could potentially undergo medical chemistry to replace disubstituted cyclohexanes and benzenes. 🔗https://hubs.ly/Q020GZbB0 #FeaturedStructureFriday #Crystallography | Cambridge Crystallographic Data Centre (CCDC)
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