USMLE High-Yield Questions on Instagram: "Video and question credit: @waqaasquraishimd Kid Rock after the methadone dose kicks in lookin’ like his QT about to start freestyling 😭⚡️ ⸻ 💡 Explanation: Methadone is a long-acting μ-opioid receptor agonist used in opioid dependence treatment. It can prolong the QT interval, predisposing to torsades de pointes — a polymorphic ventricular tachycardia that can degenerate into ventricular fibrillation if untreated. 🩺 Mechanism: Methadone blocks cardiac

Classify Rx on Instagram: "⚠️ Loperamide + Lactulose: Opposing Mechanisms 📍 Mechanism Conflict: Loperamide is an anti-diarrheal (μ-opioid agonist that slows GI motility and increases water absorption) while lactulose is an osmotic laxative (draws water into colon, increases motility)—they work directly against each other 📍No clinical indication to combine it #pharmacology"